Nicotinamide injection (1ml; 100mg)

【Drug name】

Generic name: Nicotinamide Injection

English name: Nicotinamide Injection

Chinese Pinyin: Yanxian'an Zhusheye

【Ingredients】The main ingredient of this product is: Nicotinamide.

Chemical name: 3-pyridinecarboxamide.

Molecular formula: C6H6N2O

Molecular weight: 122.13

【Properties】This product is a colorless, clear liquid.

【Indications】It is mainly used to prevent and treat arrhythmias associated with niacin deficiency, coronary heart disease, viral myocarditis, rheumatic myocarditis, and a few digitalis poisonings, and has the effect of preventing and treating heart block.

【Specifications】1ml:100mg

【Usage and Dosage】300-400mg (3-4 sticks at a time), once a day. Add 250ml of 10% glucose injection and drip intravenously. 30 days is a course of treatment.

【Adverse Reactions】Skin flushing and itching may occur after administration. Occasionally, hyperglycemia, hyperuricemia, and arrhythmia may occur.

[Contraindications] Those who are allergic to this product.

[Precautions] Nicotinamide has no vasodilatory effect and can be used when needed by patients with hypertension.

[Use in pregnant and lactating women] Overdose during pregnancy may cause teratogenicity. Lactating women should not breastfeed when using this product.

[Use in children] It is not clear yet.

[Use in the elderly] It is not clear yet.

[Drug interactions] Isoniazid and nicotinamide have antagonistic effects. Nicotinamide should be supplemented for long-term use of isoniazid.

[Overdose] It is not clear yet.

[Pharmacology and toxicology] This product is a vitamin drug. Similar to niacin, it is a component of coenzyme I and coenzyme II. It participates in the metabolic process in the body and is necessary for lipid metabolism, oxidation of tissue respiration, and glycogenolysis. But it has no vasodilatory effect. In addition, this product can prevent and treat heart block, improve sinus node function and resist experimental tachyarrhythmia, and can significantly improve the heart rate slowing and atrioventricular block caused by verapamil.

[Pharmacokinetics] It is easily absorbed by the gastrointestinal tract, and is absorbed faster by intramuscular injection. After absorption, it is converted into coenzyme in the body and distributed to tissues throughout the body, with a half-life of 45 minutes.

[Storage] Shade from light and store in a sealed container (10~30℃).

[Packaging] Colorless ampoule. 1ml per tube, 10 tubes per box.

[Validity period] 24 months

[Approval number] National Medicine Standard H44022385